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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72a3493b59d1c2d3cf4dfa1e376768b76cbb01409ec066e64f656d1c894889e6' 
  AND token = 'JdGxHgnuV7lgII7saRJCEQqnfPLnXDkY88E0JcZ01KE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}