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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1ff3e2f046416165e552e85be1301103701a1edc1b410b1670a23cc7f255907' 
  AND token = 'TOki0KYdb9LC+RrcCNqx8QdFfKzkog1cm2NPrXuYI8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}