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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f45fc3d4d43c5637c67d014826ded9d400f78566e3379f149662e3fd5a83b910' 
  AND token = 'pk/+s7e0Ixh3RkCR0SNXbRVDBlgJcjfpQKpZM+2Yd8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}