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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b37c8ff9db7da609065a4c4a8ec436cd0aff31a397ab13562b21583c3d2e54f' 
  AND token = 'TghIRKRzyTazg4tle+mA0f1SUCiwIkNe8LASXkypYIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}