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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b862b45601e3c23c230279e46d4c9886587f8849cdc9e1e87792f5e0c737d20' 
  AND token = 'sHnf5xXOz1raunWO1qhTulLkRPAIGoPb2SKy/cokAVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}