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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b42931aedfc25b6b4a2c15a620f0b065e055b05dc25d694bdbcc927de1c8f001' 
  AND token = 'vyFizDb3rERZPShHupGc+s1jdeOC8BZ9ytUgx6xCtvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}