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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e3536a153464c71febdc74e66e06ef8cd7bae07ad6dddad35425c2d63177464' 
  AND token = 'O6V3lID2L/2SzbxtuyoZGRnegW2nHw2uAz3i2vxRgiE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}