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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67f7708b163c92f1108d3955cff77f141e1e0e1c6a0fb3a12407fec58478e190' 
  AND token = 'Fxx0QXSHW8z30rEcEQ2SHzTIy/WPZlGVItBGLtXAoZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}