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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f9a04b948599aa7772779d47fec6206a670da1c434f6c2122794b2a427b3af2' 
  AND token = 'jTYDlvAzWFX9Cx0kgwIlEA3TtQMwoxEy4iGAPkURiGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}