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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64257410edcca20d88d4e93b6beaf73b44b9b348e638ad743d4d308c1fd663f3' 
  AND token = '3d/cu9rzGOFca16dovi/kuVjaPyguVD6NAl1eP8Q0tk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}