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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '074140cadf0184292fec636c0bbb232ec04442c188eb63bd32fa69cb64a72999' 
  AND token = 'DBsPwoays1oL6Z495NnsS8tpPwa85BmK3zXZCyJ8oC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}