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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '072a77d67fb2b5c86a6d99990aa87d775b4c6b86778e21051271e8e406a4b6f0' 
  AND token = 'NeQ7Z0XLId2K6RMQUhD1kSE0OkuJFn7veGDzBcKarVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}