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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77bd5e0743bff3349aaa1ec7b0ba03cd405e6ca8603d6c301b90e9a408faeba6' 
  AND token = '3pNVc6MuXTX9HGxtwmvwlD22kuC7//RvDcwxuMxPj7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}