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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c8d73f3f5ebf589069c1812ef8c3d34ab2842ca7a441e03860564a2dfb65be8' 
  AND token = 'dfexrijeBqD1O2eSV03bmjmrW7bu0UApTeWLgmbEuCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}