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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '452501563ee67e1acecf237bbba62278acc610938ffbc2bda793104aa47e4b1f' 
  AND token = '1zS3FGtSVkmq2kd3sbDCdfnAzDQ80zsbhR8I+my6s84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}