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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38c7293531bec3683f750d11637ba21a47fa2f584cf834f334a90e6d5553b166' 
  AND token = 'Zs+JzcKecCXX7FehIEDUh8/yQf00W2Qjt3fNzZQpvM8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}