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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4659ee6216bfe75a8d0e4c0e7946fca0ce19aabb8a0dd780f644e65877504642' 
  AND token = '6lmMMNlIp+YVDIP4//cGhY397IsMguwig/9HeukUqIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}