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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df3b7fed299fc1434e70569228165f24b696daddc13b27fb6762422fcc8f08eb' 
  AND token = 'ICUANOHhO1M/aD9dT3E+vFyQGUAbqZ+d42vNkMQT5eU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}