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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd7d49154cad78f187bc7e253a834f0c2483d6c2e545b677b66aa295ba1116112' 
  AND token = 'j33yA1YQaVcrYe0HaZ72qFD4Hn3izcuHPqmOPzdOIGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}