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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '458f8bf560eca983b7fb9fb52a0f31186bc6ad2d7732d1d6e8f0e5ade44a118c' 
  AND token = 'eeANAW6bz7yOGCEZ11T2devD5LXOrmWIIzFIUUaasgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}