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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb072418864c89b607c041c091894d4bbcabd5057244c140d77a2214390a80ed' 
  AND token = 'mUV8L2ccRN9O4nSWkpIAPE9bCPGbe400D3xElPYSIbA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}