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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed8a171075a30520cd7a1d0e1c5226824ab9ea022b78796412731f6478422060' 
  AND token = 'BxQ4u+j8+7tlL7BfKUneFwrhHgzV2z6Vahzi4wQPy2U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}