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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25e40f5cfdf09f9b90d131494feb905e7afb7d9172fcf33d010a964f496f049d' 
  AND token = 'y+zXyp5awahp9TyU3uZp2/UXxmcSR6qx6xJbGYoEoyc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}