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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d0336a6d4d6ea040de9525fbce3a4147ae33cacd4ec728d9f7e2ee3224dda1d' 
  AND token = 'cCZTTbgEBAWt0f/cJWWKMJhKC9GmG1UGrH0HpOalOwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}