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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0db4b461fa7da449942e8b95840435ccc3675f88ac3f05a54cf7a73da90971f5' 
  AND token = 'EaivveV7WqMPGRofyodaDv4eNKGr1/rQkQ2wz0+Ae0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}