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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1458fcace309c7420584c143f54ce364414e753a59279803a49fa8e91e6613cd' 
  AND token = '0W4WjW3dl/RLIbpsx8/FmgmZqN+Bogjrbtl1C5ms4Jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}