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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e67dcb51345682b5649f578c5aa10981d5a3d8e07bb45b17e7de8c58fb3770a4' 
  AND token = '5epDnJZZdVQN5gmEcQ8YXLq9iEc7iQjfnKm8Ro7XkK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}