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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '403a10a4fcd631b8c5363f7d790c2381b05d3bea404ee2cc253bba04401dd90d' 
  AND token = 'V/PrKlGnqzaC7qpUCy88MS3F5lgbwYL29q1GM+gG3qE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}