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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b8d4907f997cd7b8bcb4ffed164eaa0f4eb4f056f980ea5f223b681e2b33ee0' 
  AND token = '84mJIAWTVpOrAVNpDlKd6nFYPcSPvWn1Ep5DP5ZlRRw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}