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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28106245d36a3ef3ec5271206ce79cf66abb8e9519fac7d93d0acc929e92ca96' 
  AND token = '6on+NJBU8JrP/SHyJjRCI1tpMx9L4aZ9DpTi4QMDGW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}