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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bf64dd6e5e935bb3aa8b193744d19ceb08bc8f291d4118651250a9110b00e78' 
  AND token = 'Fg3iBSuOS+D6YdTSLQuR1XFZUQvGLUQQxYbeIRb/g84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}