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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15822ce1d427299963620e54555209e79e630fb73705f8e80f2ebd14dde1e149' 
  AND token = 'o+fRxKopTXqS6mP6brH/dGiG3NbmefNDYoG636UTRC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}