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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd0972d4e60c8aa08882bd2d6fa63a432a9c57e5956a99c4ae221d2e9d133631' 
  AND token = 'A+lHBT6tIgTcjiR51K2/Ng/uIcJ/vpMCdR2uXlms7Ps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}