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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ed427bb40bc1e25781ccb5673514bfd108ca27a42a7aa69a513d91df3f11550' 
  AND token = '4ywjSRiSxdK2YRwVLKfAVz/2jDuMMiNiPocZufqXzAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}