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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a19a20186fd29d017ff7e96544b0646533f209f8afb9364086224ed73d9afd78' 
  AND token = 'v3+0O3jGiTBMdfaW/OQo6jtWciwN+LQnDB9v3OM+N3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}