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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfb90d072bffd8a200862826a0c3ec5333706d116b9fc4b921f7e8e84b851410' 
  AND token = 'F4nJLsl5GbI+JK7CNSZA7LnhICqso8ReW8muNn9sK7k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}