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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b437a5f722d332a8f9f3fa7f735a36ffdd5ce6cf7018add9c84219520ba8eda3' 
  AND token = 'Nm/vfyROwPk1V3YkTub78rg34KxrYNjnCvMbWbv/KoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}