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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '20568c1c838916e981ca36df33e589ad674b762a1da01c724a22a8eff1f7c9fc' 
  AND token = '5ITyzBtu8kC16PDMm1U74pGRvhTgdROOOoaFDmXBrJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}