SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff095ad982edc095388a6d75a89ff60e1f823ef43fd763b9e7257ac5012d02c4' 
  AND token = '5JeUWBeBKVex+gPPDR/h9I/Y5uRt+VfNAkaVZ2SGWDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}