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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39263cadca21a3003824cda945464d5772643ef4a62fda52c1e2d0bbd8558635' 
  AND token = 'EleoHwzY1NnZD+HK2U706hfiHb2UyFFVw2Fa7+qwZME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}