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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7ef04429412865e49b1bbe7f795645678e7d1ce8717f1bfa85e24f5e239971b' 
  AND token = 'GbbBTnEx4NGoaBXI2NLkA9wmivdU4Zw5UwQ8wEXBlWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}