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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e53b51c4a705e5a5408085f1e5c2b3f5ef91bd7b772463ac9dc0c363040106c' 
  AND token = '2NBrY3R1Vwfx0XIi8+1SIr4QPh+HnRdIgBFb/3hfLhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}