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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9dc3e13091763acde0b6c27242e229bef0f5203e820c0c1b78e0d2387ba7488e' 
  AND token = 'VI/u8RA5TwwGCwNuNkfv+MrW19wWO4y2FmDMQ/AxWFk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}