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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd35db8917558adc7ca37573cd52dc2d1c5c4671291e7850bfcd26ea150ed94ab' 
  AND token = 'zDxcW/EVGKPbPo0USIGftAwNcVWMWZK8DL4DYyymMfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}