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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1249ac2f0c5b7b871ef94d26d86beffe3e2d247a57987ae96d28e376ac29810b' 
  AND token = '8BD9eQ+89jBmAzaRkGsrd118I4MHjsEkxZdjf7M0RD8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}