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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29fd25da43bc3542954f17bcbfd095d4190d85f7535885ae1ee1f3606a3b03fb' 
  AND token = 'DYCYszAukvOG8RZoHsWYunJkUiXf09MA+x4dAqoFBdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}