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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18aa5e73265659add0f030d3f9a63825fa283e01f10ca39e009170d65d470005' 
  AND token = 'KdzM57QIKYbYCpJKFgIcTMaN7AylcV/fkHNrCvA7vaM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}