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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7c9f932e928c6bb64a084df6c3295739dc19851f7ffea373a1f002849734340' 
  AND token = 'dM0qy8fjziXMtW57g/TckgrtRtfXewrDOLzIYtvzuZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}