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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b3b897d9bc0789b44b5445b365606794a2a8cd615a243486f62ec9586ad9df6' 
  AND token = 'eFQeV5zEiCHqZlQjaob5A8Py/jMcPgtidP4ApvaIIJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}