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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9aa22c996c8ff87dfc657bc09f2ed84677cc4f1d303b731c6e39dbc60a378b56' 
  AND token = 'yTxmfL73mAhRoBUfKkj5l2QudM7CP42Ce99g3341Uhc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}